Enhanced sensitivity to cisplatin and gemcitabine in Brca1-deficient murine mammary epithelial cells

BACKGROUND: Breast cancers due to germline mutations or altered expression of the BRCA1 gene associate with an aggressive clinical course and frequently exhibit a "triple-negative" phenotype, i.e. lack of expression of the estrogen and progesterone hormone receptors and lack of overexpress...

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Detalles Bibliográficos
Autores principales: Alli, Elizabeth, Sharma, Vandana B, Hartman, Anne-Renee, Lin, Patrick S, McPherson, Lisa, Ford, James M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146825/
https://www.ncbi.nlm.nih.gov/pubmed/21771338
http://dx.doi.org/10.1186/1471-2210-11-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146825/
https://www.ncbi.nlm.nih.gov/pubmed/21771338
http://dx.doi.org/10.1186/1471-2210-11-7

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