Glioblastoma-derived Leptin Induces Tube Formation and Growth of Endothelial Cells: Comparison with VEGF Effects

BACKGROUND: Leptin is a pleiotropic hormone whose mitogenic and angiogenic activity has been implicated in the development and progression of several malignancies, including brain tumors. In human brain cancer, especially in glioblastoma multiforme (GBM), leptin and its receptor (ObR) are overexpres...

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Detalles Bibliográficos
Autores principales: Ferla, Rita, Bonomi, Maria, Otvos, Laszlo, Surmacz, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146945/
https://www.ncbi.nlm.nih.gov/pubmed/21771332
http://dx.doi.org/10.1186/1471-2407-11-303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146945/
https://www.ncbi.nlm.nih.gov/pubmed/21771332
http://dx.doi.org/10.1186/1471-2407-11-303

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