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Selective Glucocorticoid Receptor (GR-II) Antagonist Reduces Body Weight Gain in Mice

Previous research has shown that mifepristone can prevent and reverse weight gain in animals and human subjects taking antipsychotic medications. This proof-of-concept study tested whether a more potent and selective glucocorticoid receptor antagonist could block dietary-induced weight gain and incr...

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Detalles Bibliográficos
Autores principales: Asagami, Tomoko, Belanoff, Joseph K., Azuma, Junya, Blasey, Christine M., Clark, Robin D., Tsao, Philip S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146995/
https://www.ncbi.nlm.nih.gov/pubmed/21811679
http://dx.doi.org/10.1155/2011/235389