Structural Coupling between RNA Polymerase Composition and DNA Supercoiling in Coordinating Transcription: a Global Role for the Omega Subunit?

In growing bacterial cells, the global reorganization of transcription is associated with alterations of RNA polymerase composition and the superhelical density of the DNA. However, the existence of any regulatory device coordinating these changes remains elusive. Here we show that in an exponential...

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Detalles Bibliográficos
Autores principales: Geertz, Marcel, Travers, Andrew, Mehandziska, Sanja, Sobetzko, Patrick, Chandra Janga, Sarath, Shimamoto, Nobuo, Muskhelishvili, Georgi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147163/
https://www.ncbi.nlm.nih.gov/pubmed/21810966
http://dx.doi.org/10.1128/mBio.00034-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147163/
https://www.ncbi.nlm.nih.gov/pubmed/21810966
http://dx.doi.org/10.1128/mBio.00034-11

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