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Structural Coupling between RNA Polymerase Composition and DNA Supercoiling in Coordinating Transcription: a Global Role for the Omega Subunit?
In growing bacterial cells, the global reorganization of transcription is associated with alterations of RNA polymerase composition and the superhelical density of the DNA. However, the existence of any regulatory device coordinating these changes remains elusive. Here we show that in an exponential...
Autores principales: | Geertz, Marcel, Travers, Andrew, Mehandziska, Sanja, Sobetzko, Patrick, Chandra Janga, Sarath, Shimamoto, Nobuo, Muskhelishvili, Georgi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147163/ https://www.ncbi.nlm.nih.gov/pubmed/21810966 http://dx.doi.org/10.1128/mBio.00034-11 |
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