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Lipopolysaccharide (LPS) Inner-Core Phosphates Are Required for Complete LPS Synthesis and Transport to the Outer Membrane in Pseudomonas aeruginosa PAO1

Gram-negative outer membrane (OM) integrity is maintained in part by Mg(2+) cross-links between phosphates on lipid A and on core sugars of adjacent lipopolysaccharide (LPS) molecules. In contrast to other Gram-negative bacteria, waaP, encoding an inner-core kinase, could not be inactivated in Pseud...

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Detalles Bibliográficos
Autores principales: DeLucia, Angela M., Six, David A., Caughlan, Ruth E., Gee, Patricia, Hunt, Ian, Lam, Joseph S., Dean, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147165/
https://www.ncbi.nlm.nih.gov/pubmed/21810964
http://dx.doi.org/10.1128/mBio.00142-11