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Tumor-Derived Syndecan-1 Mediates Distal Cross-Talk with Bone that Enhances Osteoclastogenesis

Tumor-stimulated bone resorption fuels tumor growth and marks a dramatic decline in the health and prognosis of breast cancer patients. Identifying mechanisms that mediate cross-talk between tumor and bone remains a key challenge. We previously demonstrated that breast cancer cells expressing high l...

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Detalles Bibliográficos
Autores principales: Kelly, Thomas, Suva, Larry J, Nicks, Kristy M, MacLeod, Veronica, Sanderson, Ralph D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148092/
https://www.ncbi.nlm.nih.gov/pubmed/20200931
http://dx.doi.org/10.1002/jbmr.16