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Aurora-A Interacts with AP-2α and Down Regulates Its Transcription Activity

Aurora-A is a serine/threonine protein kinase and plays an important role in the control of mitotic progression. Dysregulated expression of Aurora-A impairs centrosome separation and maturation, which lead to disrupted cell cycle progression and tumorigenesis. However, the molecular mechanism by whi...

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Detalles Bibliográficos
Autores principales: Zou, Lihui, Sun, Yimin, Wang, Mingrong, Zhan, Qimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148253/
https://www.ncbi.nlm.nih.gov/pubmed/21829699
http://dx.doi.org/10.1371/journal.pone.0023110