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The effect of substance P on asthmatic rat airway smooth muscle cell proliferation, migration, and cytoplasmic calcium concentration in vitro

Airway remodeling and airway hyper-responsiveness are prominent features of asthma. Neurogenic inflammation participates in the development of asthma. Neurokinin substance P acts by binding to neurokinin-1 receptor (NK-1R). Airway smooth muscle cells (ASMC) are important effector cells in asthma. In...

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Detalles Bibliográficos
Autores principales: Li, Miao, Shang, Yun-Xiao, Wei, Bing, Yang, Yun-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148551/
https://www.ncbi.nlm.nih.gov/pubmed/21777465
http://dx.doi.org/10.1186/1476-9255-8-18