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The human RECQ1 helicase is highly expressed in glioblastoma and plays an important role in tumor cell proliferation
BACKGROUND: RecQ helicases play an essential role in the maintenance of genome stability. In humans, loss of RecQ helicase function is linked with predisposition to cancer and/or premature ageing. Current data show that the specific depletion of the human RECQ1 helicase leads to mitotic catastrophe...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148559/ https://www.ncbi.nlm.nih.gov/pubmed/21752281 http://dx.doi.org/10.1186/1476-4598-10-83 |