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Aurora Kinase A expression is associated with lung cancer histological-subtypes and with tumor de-differentiation

BACKGROUND: Aurora kinase A (AURKA) is a member of serine/threonine kinase family. Several kinases belonging to this family are activated in the G2/M phase of the cell cycle being involved in mitotic chromosomal segregation. AURKA overexpression is significantly associated with neoplastic transforma...

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Detalles Bibliográficos
Autores principales: Lo Iacono, Marco, Monica, Valentina, Saviozzi, Silvia, Ceppi, Paolo, Bracco, Enrico, Papotti, Mauro, Scagliotti, Giorgio V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148570/
https://www.ncbi.nlm.nih.gov/pubmed/21718475
http://dx.doi.org/10.1186/1479-5876-9-100