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Palladium‐Catalyzed Aryl Amination Reactions of 6‐Bromo‐ and 6‐Chloropurine Nucleosides

Palladium‐catalyzed C—N bond forming reactions of 6‐bromo‐ as well as 6‐chloropurine ribonucleosides and the 2′‐deoxy analogues with arylamines are described. Efficient conversions were observed with palladium(II) acetate/Xantphos/cesium carbonate, in toluene at 100 °C. Reactions of the bromonucleos...

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Detalles Bibliográficos
Autores principales: Thomson, Paul F., Lagisetty, Pallavi, Balzarini, Jan, De Clercq, Erik, Lakshman, Mahesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY‐VCH Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148652/
https://www.ncbi.nlm.nih.gov/pubmed/21818182
http://dx.doi.org/10.1002/adsc.200900728