Phenobarbital but Not Diazepam Reduces AMPA/kainate Receptor Mediated Currents and Exerts Opposite Actions on Initial Seizures in the Neonatal Rat Hippocampus

Diazepam (DZP) and phenobarbital (PB) are extensively used as first and second line drugs to treat acute seizures in neonates and their actions are thought to be mediated by increasing the actions of GABAergic signals. Yet, their efficacy is variable with occasional failure or even aggravation of re...

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Detalles Bibliográficos
Autores principales: Nardou, Romain, Yamamoto, Sumii, Bhar, Asma, Burnashev, Nail, Ben-Ari, Yehezkel, Khalilov, Ilgam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148783/
https://www.ncbi.nlm.nih.gov/pubmed/21847371
http://dx.doi.org/10.3389/fncel.2011.00016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148783/
https://www.ncbi.nlm.nih.gov/pubmed/21847371
http://dx.doi.org/10.3389/fncel.2011.00016

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