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Preparation and evaluation of lidocaine hydrochloride in cyclodextrin inclusion complexes for development of stable gel in association with chlorhexidine gluconate for urogenital use

Inclusions of lidocaine hydrochloride in cyclodextrins were prepared to obtain stable complexes compatible for association with chlorhexidine in a new gel formulation for use in urogenital applications. Two cyclodextrins, β-cyclodextrin and methyl-β-cyclodextrin, were used for encapsulating lidocain...

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Detalles Bibliográficos
Autores principales: Soares da Silva, Luiz Francisco Jones, do Carmo, Flavia Almada, de Almeida Borges, Vinicius Raphael, Monteiro, Lidiane Mota, Rodrigues, Carlos Rangel, Cabral, Lúcio Mendes, de Sousa, Valeria Pereira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148842/
https://www.ncbi.nlm.nih.gov/pubmed/21822378
http://dx.doi.org/10.2147/IJN.S20409