Liposomes containing glycocholate as potential oral insulin delivery systems: preparation, in vitro characterization, and improved protection against enzymatic degradation

BACKGROUND: Oral delivery of insulin is challenging and must overcome the barriers of gastric and enzymatic degradation as well as low permeation across the intestinal epithelium. The present study aimed to develop a liposomal delivery system containing glycocholate as an enzyme inhibitor and permea...

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Detalles Bibliográficos
Autores principales: Niu, Mengmeng, Lu, Yi, Hovgaard, Lars, Wu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148843/
https://www.ncbi.nlm.nih.gov/pubmed/21822379
http://dx.doi.org/10.2147/IJN.S19917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148843/
https://www.ncbi.nlm.nih.gov/pubmed/21822379
http://dx.doi.org/10.2147/IJN.S19917

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