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Update on treatment options for Lambert–Eaton myasthenic syndrome: focus on use of amifampridine

In Lambert–Eaton myasthenic syndrome (LEMS), antibodies against presynaptic voltage-gated calcium channels reduce the quantal release of acetylcholine, causing muscle weakness and autonomic dysfunction. More than half of the affected patients have associated small cell lung cancer, and thorough scre...

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Detalles Bibliográficos
Autores principales: Lindquist, Sabine, Stangel, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148925/
https://www.ncbi.nlm.nih.gov/pubmed/21822385
http://dx.doi.org/10.2147/NDT.S10464