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Update on treatment options for Lambert–Eaton myasthenic syndrome: focus on use of amifampridine
In Lambert–Eaton myasthenic syndrome (LEMS), antibodies against presynaptic voltage-gated calcium channels reduce the quantal release of acetylcholine, causing muscle weakness and autonomic dysfunction. More than half of the affected patients have associated small cell lung cancer, and thorough scre...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148925/ https://www.ncbi.nlm.nih.gov/pubmed/21822385 http://dx.doi.org/10.2147/NDT.S10464 |