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Differential effect of CLK SR Kinases on HIV-1 gene expression: potential novel targets for therapy

BACKGROUND: RNA processing plays a critical role in the replication of HIV-1, regulated in part through the action of host SR proteins. To explore the impact of modulating SR protein activity on virus replication, the effect of increasing or inhibiting the activity of the Cdc2-like kinase (CLK) fami...

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Detalles Bibliográficos
Autores principales: Wong, Raymond, Balachandran, Ahalya, Mao, Annie YQ, Dobson, Wendy, Gray-Owen, Scott, Cochrane, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148977/
https://www.ncbi.nlm.nih.gov/pubmed/21682887
http://dx.doi.org/10.1186/1742-4690-8-47