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Worldwide Genetic Variability of the Duffy Binding Protein: Insights into Plasmodium vivax Vaccine Development

The dependence of Plasmodium vivax on invasion mediated by Duffy binding protein (DBP) makes this protein a prime candidate for development of a vaccine. However, the development of a DBP-based vaccine might be hampered by the high variability of the protein ligand (DBP(II)), known to bias the immun...

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Detalles Bibliográficos
Autores principales: Nóbrega de Sousa, Taís, Carvalho, Luzia Helena, Alves de Brito, Cristiana Ferreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149059/
https://www.ncbi.nlm.nih.gov/pubmed/21829672
http://dx.doi.org/10.1371/journal.pone.0022944