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Study on Phylogenetic Relationships, Variability, and Correlated Mutations in M2 Proteins of Influenza Virus A

M2 channel, an influenza virus transmembrane protein, serves as an important target for antiviral drug design. There are still discordances concerning the role of some residues involved in proton transfer as well as the mechanism of inhibition by commercial drugs. The viral M2 proteins show high con...

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Detalles Bibliográficos
Autores principales: Le, Ly, Leluk, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149066/
https://www.ncbi.nlm.nih.gov/pubmed/21829678
http://dx.doi.org/10.1371/journal.pone.0022970