Uncoordinated Loss of Chromatid Cohesion Is a Common Outcome of Extended Metaphase Arrest

Chromosome segregation requires coordinated separation of sister chromatids following biorientation of all chromosomes on the mitotic spindle. Chromatid separation at the metaphase-to-anaphase transition is accomplished by cleavage of the cohesin complex that holds chromatids together. Here we show...

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Detalles Bibliográficos
Autores principales: Stevens, Deanna, Gassmann, Reto, Oegema, Karen, Desai, Arshad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149067/
https://www.ncbi.nlm.nih.gov/pubmed/21829677
http://dx.doi.org/10.1371/journal.pone.0022969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149067/
https://www.ncbi.nlm.nih.gov/pubmed/21829677
http://dx.doi.org/10.1371/journal.pone.0022969

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