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MyD88 and STING Signaling Pathways Are Required for IRF3-Mediated IFN-β Induction in Response to Brucella abortus Infection

Type I interferons (IFNs) are cytokines that orchestrate diverse immune responses to viral and bacterial infections. Although typically considered to be most important molecules in response to viruses, type I IFNs are also induced by most, if not all, bacterial pathogens. In this study, we addressed...

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Detalles Bibliográficos
Autores principales: de Almeida, Leonardo A., Carvalho, Natalia B., Oliveira, Fernanda S., Lacerda, Thais L. S., Vasconcelos, Anilton C., Nogueira, Lucas, Bafica, Andre, Silva, Aristóbolo M., Oliveira, Sergio C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149075/
https://www.ncbi.nlm.nih.gov/pubmed/21829705
http://dx.doi.org/10.1371/journal.pone.0023135