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Sox9-Haploinsufficiency Causes Glucose Intolerance in Mice

The HMG box transcription factor Sox9 plays a critical role in progenitor cell expansion during pancreas organogenesis and is required for proper endocrine cell development in the embryo. Based on in vitro studies it has been suggested that Sox9 controls expression of a network of important developm...

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Detalles Bibliográficos
Autores principales: Dubois, Claire L., Shih, Hung Ping, Seymour, Philip A., Patel, Nisha A., Behrmann, James M., Ngo, Victoria, Sander, Maike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149078/
https://www.ncbi.nlm.nih.gov/pubmed/21829703
http://dx.doi.org/10.1371/journal.pone.0023131