Cargando…

Sox9-Haploinsufficiency Causes Glucose Intolerance in Mice

The HMG box transcription factor Sox9 plays a critical role in progenitor cell expansion during pancreas organogenesis and is required for proper endocrine cell development in the embryo. Based on in vitro studies it has been suggested that Sox9 controls expression of a network of important developm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dubois, Claire L., Shih, Hung Ping, Seymour, Philip A., Patel, Nisha A., Behrmann, James M., Ngo, Victoria, Sander, Maike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149078/ https://www.ncbi.nlm.nih.gov/pubmed/21829703 http://dx.doi.org/10.1371/journal.pone.0023131

Ejemplares similares

Case report: Cystic hygroma accompanied with campomelic dysplasia in the first trimester caused by haploinsufficiency with SOX9 deletion
por: Liu, Xijing, et al.
Publicado: (2022)

Profilin-1 Haploinsufficiency Protects Against Obesity-Associated Glucose Intolerance and Preserves Adipose Tissue Immune Homeostasis
por: Romeo, Giulio R., et al.
Publicado: (2013)

SOX2 haploinsufficiency promotes impaired vision at advanced age
por: Moreno-Cugnon, Leire, et al.
Publicado: (2018)

SOX2 haploinsufficiency is associated with slow progressing hypothalamo-pituitary tumours
por: Alatzoglou, Kyriaki S, et al.
Publicado: (2011)

Mouse Sox17 haploinsufficiency leads to female subfertility due to impaired implantation
por: Hirate, Yoshikazu, et al.
Publicado: (2016)

Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration
por: Barrionuevo, Francisco J, et al.
Publicado: (2016)

METABOLIC SYNDROME, GLUCOSE INTOLERANCE, AND PHYSICAL RESILIENCE
por: Kalyani, Rita, et al.
Publicado: (2022)

Transformation of SOX9(+) cells by Pten deletion synergizes with steatotic liver injury to drive development of hepatocellular and cholangiocarcinoma
por: Chen, Jingyu, et al.
Publicado: (2021)

The role of Sox9 in mouse mammary gland development and maintenance of mammary stem and luminal progenitor cells
por: Malhotra, Gautam K, et al.
Publicado: (2014)

Proinsulin is sensitive to reflect glucose intolerance
por: Nakamura, Akinobu, et al.
Publicado: (2019)

Adipocyte CAMK2 deficiency improves obesity-associated glucose intolerance
por: Dai, Wen, et al.
Publicado: (2021)

Predicting glucose intolerance with normal fasting plasma glucose by the components of the metabolic syndrome
por: Pei, Dee, et al.
Publicado: (2007)

Partial Inhibition of Insulin Secretion Results in Glucose Intolerance but Not Hyperglucagonemia
por: Ramanathan, Ranjani P., et al.
Publicado: (2011)

PLIN1 Haploinsufficiency Causes a Favorable Metabolic Profile
por: Patel, Kashyap A, et al.
Publicado: (2022)

Historical Perspective: Beginnings of the β-Cell: Current Perspectives in β-Cell Development
por: Seymour, Philip A., et al.
Publicado: (2011)

Glucose Intolerance in Pregnancy and Future Risk of Pre-Diabetes or Diabetes
por: Retnakaran, Ravi, et al.
Publicado: (2008)

Blueberries’ Impact on Insulin Resistance and Glucose Intolerance
por: Stull, April J.
Publicado: (2016)

The SOXE transcription factors—SOX8, SOX9 and SOX10—share a bi-partite transactivation mechanism
por: Haseeb, Abdul, et al.
Publicado: (2019)

(−)-Epicatechin Reverses Glucose Intolerance in Rats Housed at Thermoneutrality
por: Chun, Ji Hye, et al.
Publicado: (2022)

Msx1 haploinsufficiency modifies the Pax9-deficient cardiovascular phenotype
por: Khasawneh, Ramada R., et al.
Publicado: (2021)

Nonnutritive sweeteners and glucose intolerance: Where do we go from here?
por: Nobs, Samuel Philip, et al.
Publicado: (2023)

PLIN1 Haploinsufficiency Is Not Associated With Lipodystrophy
por: Laver, Thomas W, et al.
Publicado: (2018)

Mesoderm-specific Stat3 deletion affects expression of Sox9 yielding Sox9-dependent phenotypes
por: Hall, Michael D., et al.
Publicado: (2017)

Diabetes and COVID-19: Diseases of racial, social and glucose intolerance
por: Chowdhury, Tahseen A
Publicado: (2021)

Trio Haploinsufficiency Causes Neurodevelopmental Disease–Associated Deficits
por: Katrancha, Sara Marie, et al.
Publicado: (2019)

Intestinal Ralstonia pickettii augments glucose intolerance in obesity
por: Udayappan, Shanthadevi D., et al.
Publicado: (2017)

Exportin 4 Interacts with Sox9 through the HMG Box and Inhibits the DNA Binding of Sox9
por: Tsuchiya, Megumi, et al.
Publicado: (2011)

Structure of the C9orf72 Arf GAP complex haploinsufficient in ALS and FTD
por: Su, Ming-Yuan, et al.
Publicado: (2020)

Exenatide improves glucocorticoid-induced glucose intolerance in mice
por: Zhao, Ruiying, et al.
Publicado: (2011)

Fat Distribution and Glucose Intolerance Among Greenland Inuit
por: Jørgensen, Marit Eika, et al.
Publicado: (2013)

Fasting and rapamycin: diabetes versus benevolent glucose intolerance
por: Blagosklonny, Mikhail V.
Publicado: (2019)

Barriers to Postpartum Glucose Intolerance Screening in an Italian Population
por: Quaresima, Paola, et al.
Publicado: (2018)

Circulating myokine levels in different stages of glucose intolerance
por: Park, Kahui, et al.
Publicado: (2020)

Hyperleptinaemia and its Association with Postprandial Hypertriglyceridemia and Glucose Intolerance
por: Aslam, M., et al.
Publicado: (2021)

PTEN haploinsufficiency and hemangiosarcoma
Publicado: (2012)

Determinants of Impaired Fasting Glucose Versus Glucose Intolerance in Polycystic Ovary Syndrome
por: Karakas, Sidika E., et al.
Publicado: (2010)

Glucose Homeostatic Law: Insulin Clearance Predicts the Progression of Glucose Intolerance in Humans
por: Ohashi, Kaoru, et al.
Publicado: (2015)

Oestrogen shuts the door on SOX9
por: Mork, Lindsey, et al.
Publicado: (2010)

SOX9: Advances in Gynecological Malignancies
por: Chen, Huan, et al.
Publicado: (2021)

Oral Glucose Tolerance Test for the Screening of Glucose Intolerance Long Term Post‐Heart Transplantation
por: Roest, Stefan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_lpscq8kfalf8epfgsds5le53eq