Abrogation of CD30 and OX40 signals prevents autoimmune disease in FoxP3-deficient mice

Our previous studies have implicated signaling through the tumor necrosis family receptors OX40 and CD30 as critical for maintaining CD4 memory responses. We show that signals through both molecules are also required for CD4 effector-mediated autoimmune tissue damage. Under normal circumstances, mal...

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Detalles Bibliográficos
Autores principales: M.Gaspal, Fabrina, Withers, David, Saini, Manoj, Bekiaris, Vasileios, McConnell, Fiona M., White, Andrea, Khan, Mahmood, Yagita, Hideo, Walker, Lucy S.K., Anderson, Graham, Lane, Peter J.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149223/
https://www.ncbi.nlm.nih.gov/pubmed/21788408
http://dx.doi.org/10.1084/jem.20101484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149223/
https://www.ncbi.nlm.nih.gov/pubmed/21788408
http://dx.doi.org/10.1084/jem.20101484

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