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Abrogation of CD30 and OX40 signals prevents autoimmune disease in FoxP3-deficient mice
Our previous studies have implicated signaling through the tumor necrosis family receptors OX40 and CD30 as critical for maintaining CD4 memory responses. We show that signals through both molecules are also required for CD4 effector-mediated autoimmune tissue damage. Under normal circumstances, mal...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149223/ https://www.ncbi.nlm.nih.gov/pubmed/21788408 http://dx.doi.org/10.1084/jem.20101484 |