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Chemokine receptor CXCR3 facilitates CD8(+) T cell differentiation into short-lived effector cells leading to memory degeneration

Strength of inflammatory stimuli during the early expansion phase plays a crucial role in the effector versus memory cell fate decision of CD8(+) T cells. But it is not known how early lymphocyte distribution after infection has an impact on this process. We demonstrate that the chemokine receptor C...

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Detalles Bibliográficos
Autores principales: Kurachi, Makoto, Kurachi, Junko, Suenaga, Fumiko, Tsukui, Tatsuya, Abe, Jun, Ueha, Satoshi, Tomura, Michio, Sugihara, Kei, Takamura, Shiki, Kakimi, Kazuhiro, Matsushima, Kouji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149224/
https://www.ncbi.nlm.nih.gov/pubmed/21788406
http://dx.doi.org/10.1084/jem.20102101