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Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors
Whereas maintenance of hematopoietic stem cells (HSCs) is a requisite for life, uncontrolled expansion of HSCs might enhance the propensity for leukemic transformation. Accordingly, HSC numbers are tightly regulated. The identification of physical cellular HSC niches has underscored the importance o...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149225/ https://www.ncbi.nlm.nih.gov/pubmed/21768269 http://dx.doi.org/10.1084/jem.20110752 |