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Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors

Whereas maintenance of hematopoietic stem cells (HSCs) is a requisite for life, uncontrolled expansion of HSCs might enhance the propensity for leukemic transformation. Accordingly, HSC numbers are tightly regulated. The identification of physical cellular HSC niches has underscored the importance o...

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Detalles Bibliográficos
Autores principales:	Pronk, Cornelis J.H., Veiby, Ole Petter, Bryder, David, Jacobsen, Sten Eirik W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2011
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149225/ https://www.ncbi.nlm.nih.gov/pubmed/21768269 http://dx.doi.org/10.1084/jem.20110752

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