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Rhomboid Family Pseudoproteases Use the ER Quality Control Machinery to Regulate Intercellular Signaling
Intramembrane proteolysis governs many cellular control processes, but little is known about how intramembrane proteases are regulated. iRhoms are a conserved subfamily of proteins related to rhomboid intramembrane serine proteases that lack key catalytic residues. We have used a combination of gene...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149277/ https://www.ncbi.nlm.nih.gov/pubmed/21439629 http://dx.doi.org/10.1016/j.cell.2011.02.047 |