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Dimerumic Acid Inhibits SW620 Cell Invasion by Attenuating H(2)O(2)-Mediated MMP-7 Expression via JNK/C-Jun and ERK/C-Fos Activation in an AP-1-Dependent Manner

Reactive oxygen species (ROS) such as hydrogen peroxide (H(2)O(2)) in the tumor microenvironment play important roles in tumor invasion and metastasis. Recently, ROS have been reported to cause a significant increase in the production and expression of matrix metalloproteinase (MMP)-7, which is clos...

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Detalles Bibliográficos
Autores principales: Ho, Bing-Ying, Wu, Yao-Ming, Chang, King-Jen, Pan, Tzu-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149281/
https://www.ncbi.nlm.nih.gov/pubmed/21814482