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Long-term Cultured Human Neural Stem Cells Undergo Spontaneous Transformation to Tumor-Initiating Cells

In this report, we describe the spontaneous malignant transformation of long-term cultured human fetal striatum neural stem cells (hsNSCs, passage 17). After subcutaneous transplantation of long-term cultured hsNSCs into immunodeficient nude mice, 2 out of 15 mice formed xenografts which expressed n...

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Detalles Bibliográficos
Autores principales: Wu, Weihua, He, Qihua, Li, Xiaoxia, Zhang, Xiaoyan, Lu, Aili, Ge, Ruimin, Zhen, HongYing, Chang, Alfred E., Li, Qiao, Shen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149283/
https://www.ncbi.nlm.nih.gov/pubmed/21814484