2-Aminophenoxazine-3-one and 2-amino-4,4α-dihydro-4α,7-dimethyl-3H-phenoxazine-3-one cause cellular apoptosis by reducing higher intracellular pH in cancer cells

We examined intracellular pH (pHi) of ten cancer cell lines derived from different organs and two normal cell lines including human embryonic lung fibroblast cells (HEL) and human umbilical vein endothelial cells (HUVEC) in vitro, and found that pHi of most of these cancer cells was evidently higher...

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Detalles Bibliográficos
Autores principales: CHE, Xiao-Fang, ZHENG, Chun-Lei, AKIYAMA, Shin-Ichi, TOMODA, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149379/
https://www.ncbi.nlm.nih.gov/pubmed/21558757
http://dx.doi.org/10.2183/pjab.87.199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149379/
https://www.ncbi.nlm.nih.gov/pubmed/21558757
http://dx.doi.org/10.2183/pjab.87.199

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