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Involvement of Flt-1 (VEGF receptor-1) in cancer and preeclampsia

We previously isolated a novel tyrosine kinase receptor, Flt-1, now known as VEGF-receptor (VEGFR)-1. The VEGF–VEGFR system plays a pivotal role in not only physiological but also pathological angiogenesis. We examined the role of Flt-1 in carcinogenesis using Flt-1-signal-deficient (Flt-1 TK−/−) mi...

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Detalles Bibliográficos
Autor principal: SHIBUYA, Masabumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149381/
https://www.ncbi.nlm.nih.gov/pubmed/21558755
http://dx.doi.org/10.2183/pjab.87.167