Cargando…
Local constraints in either the GluN1 or GluN2 subunit equally impair NMDA receptor pore opening
The defining functional feature of N-methyl-d-aspartate (NMDA) receptors is activation gating, the energetic coupling of ligand binding into opening of the associated ion channel pore. NMDA receptors are obligate heterotetramers typically composed of glycine-binding GluN1 and glutamate-binding GluN2...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149435/ https://www.ncbi.nlm.nih.gov/pubmed/21746848 http://dx.doi.org/10.1085/jgp.201110623 |