R1 in the Shaker S4 occupies the gating charge transfer center in the resting state

During voltage-dependent activation in Shaker channels, four arginine residues in the S4 segment (R1–R4) cross the transmembrane electric field. It has been proposed that R1–R4 movement is facilitated by a “gating charge transfer center” comprising a phenylalanine (F290) in S2 plus two acidic residu...

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Detalles Bibliográficos
Autores principales: Lin, Meng-chin A., Hsieh, Jui-Yi, Mock, Allan F., Papazian, Diane M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149438/
https://www.ncbi.nlm.nih.gov/pubmed/21788609
http://dx.doi.org/10.1085/jgp.201110642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149438/
https://www.ncbi.nlm.nih.gov/pubmed/21788609
http://dx.doi.org/10.1085/jgp.201110642

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