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Dynamical Basis for Drug Resistance of HIV-1 Protease
BACKGROUND: Protease inhibitors designed to bind to protease have become major anti-AIDS drugs. Unfortunately, the emergence of viral mutations severely limits the long-term efficiency of the inhibitors. The resistance mechanism of these diversely located mutations remains unclear. RESULTS: Here I u...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149572/ https://www.ncbi.nlm.nih.gov/pubmed/21740562 http://dx.doi.org/10.1186/1472-6807-11-31 |