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Bias detection and correction in RNA-Sequencing data

BACKGROUND: High throughput sequencing technology provides us unprecedented opportunities to study transcriptome dynamics. Compared to microarray-based gene expression profiling, RNA-Seq has many advantages, such as high resolution, low background, and ability to identify novel transcripts. Moreover...

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Detalles Bibliográficos
Autores principales: Zheng, Wei, Chung, Lisa M, Zhao, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149584/
https://www.ncbi.nlm.nih.gov/pubmed/21771300
http://dx.doi.org/10.1186/1471-2105-12-290