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BBC3 (PUMA) regulates developmental apoptosis but not axonal injury induced death in the retina
BACKGROUND: Naturally occurring apoptosis is a developmental process that shapes the retina by eliminating overproduced neurons. In the absence of the proapoptotic Bcl-2 family member BAX, developmental apoptosis in the retina is disrupted and extra neurons survive. It is unknown how BAX is activate...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149592/ https://www.ncbi.nlm.nih.gov/pubmed/21762490 http://dx.doi.org/10.1186/1750-1326-6-50 |