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Nicotinamide Phosphoribosyltransferase/Visfatin Does Not Catalyze Nicotinamide Mononucleotide Formation in Blood Plasma

Nicotinamide (Nam) phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme in mammalian NAD synthesis, catalyzing nicotinamide mononucleotide (NMN) formation from Nam and 5-phosphoribosyl 1-pyrophosphate (PRPP). NAMPT has also been described as an adipocytokine visfatin with a variety of actio...

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Detalles Bibliográficos
Autores principales: Hara, Nobumasa, Yamada, Kazuo, Shibata, Tomoko, Osago, Harumi, Tsuchiya, Mikako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149623/
https://www.ncbi.nlm.nih.gov/pubmed/21826208
http://dx.doi.org/10.1371/journal.pone.0022781