Cargando…

Nicotinamide Phosphoribosyltransferase/Visfatin Does Not Catalyze Nicotinamide Mononucleotide Formation in Blood Plasma

Nicotinamide (Nam) phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme in mammalian NAD synthesis, catalyzing nicotinamide mononucleotide (NMN) formation from Nam and 5-phosphoribosyl 1-pyrophosphate (PRPP). NAMPT has also been described as an adipocytokine visfatin with a variety of actio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hara, Nobumasa, Yamada, Kazuo, Shibata, Tomoko, Osago, Harumi, Tsuchiya, Mikako
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149623/ https://www.ncbi.nlm.nih.gov/pubmed/21826208 http://dx.doi.org/10.1371/journal.pone.0022781

Ejemplares similares

Quantitative analysis of the effects of nicotinamide phosphoribosyltransferase induction on the rates of NAD(+) synthesis and breakdown in mammalian cells using stable isotope-labeling combined with mass spectrometry
por: Hara, Nobumasa, et al.
Publicado: (2019)

Visfatin Impairs Endothelium-Dependent Relaxation in Rat and Human Mesenteric Microvessels through Nicotinamide Phosphoribosyltransferase Activity
por: Vallejo, Susana, et al.
Publicado: (2011)

Antioxidant effect of nicotinamide mononucleotide in tendinopathy
por: Yamaura, Kohei, et al.
Publicado: (2022)

Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase/Visfatin Enzymatic Activity Identifies a New Inflammatory Pathway Linked to NAD
por: Busso, Nathalie, et al.
Publicado: (2008)

NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells
por: Ratajczak, Joanna, et al.
Publicado: (2016)

Metabolic engineering of Escherichia coli for biosynthesis of β‐nicotinamide mononucleotide from nicotinamide
por: Liu, Yang, et al.
Publicado: (2021)

Nicotinamide phosphoribosyltransferase leukocyte overexpression in Graves’ opthalmopathy
por: Sawicka-Gutaj, Nadia, et al.
Publicado: (2016)

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells
por: Fletcher, Rachel S., et al.
Publicado: (2017)

Identification of the nicotinamide mononucleotide adenylyltransferase of Trypanosoma cruzi
por: Niño, Carlos H, et al.
Publicado: (2015)

Correction: Antioxidant effect of nicotinamide mononucleotide in tendinopathy
por: Yamaura, Kohei, et al.
Publicado: (2022)

Oral Administration of Nicotinamide Mononucleotide Increases Nicotinamide Adenine Dinucleotide Level in an Animal Brain
por: Ramanathan, Chidambaram, et al.
Publicado: (2022)

Extracellular nicotinamide phosphoribosyltransferase, a new cancer metabokine
por: Grolla, Ambra A, et al.
Publicado: (2016)

Metabolic and molecular insights into an essential role of nicotinamide phosphoribosyltransferase
por: Zhang, Li Q, et al.
Publicado: (2017)

NAD+ Precursors Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR): Potential Dietary Contribution to Health
por: Alegre, Gabriela Fabiana Soares, et al.
Publicado: (2023)

Enhanced Production of β-Nicotinamide Mononucleotide with Exogenous Nicotinamide Addition in Saccharomyces boulardii-YS01
por: Song, Meijie, et al.
Publicado: (2023)

β-nicotinamide mononucleotide (NMN) production in Escherichia coli
por: Marinescu, George Cătălin, et al.
Publicado: (2018)

Nicotinamide mononucleotide production by fructophilic lactic acid bacteria
por: Sugiyama, Kazane, et al.
Publicado: (2021)

Nicotinamide mononucleotide ameliorates senescence in alveolar epithelial cells
por: Fang, Tingting, et al.
Publicado: (2021)

Nicotinamide mononucleotide improves spermatogenic function in streptozotocin-induced diabetic mice via modulating the glycolysis pathway: Nicotinamide mononucleotide improves spermatogenic function
por: Ma, Duo, et al.
Publicado: (2022)

Extracellular nicotinamide phosphoribosyltransferase (NAMPT/visfatin) inhibits insulin-like growth factor-1 signaling and proteoglycan synthesis in human articular chondrocytes
por: Yammani, Raghunatha R, et al.
Publicado: (2012)

Nicotinamide Phosphoribosyltransferase May Be Involved in Age-Related Brain Diseases
por: Liu, Li-Ying, et al.
Publicado: (2012)

Prognostic value of serum nicotinamide phosphoribosyltransferase in patients with bladder cancer
por: Zhang, Kui, et al.
Publicado: (2014)

Structural Basis of Beneficial Design for Effective Nicotinamide Phosphoribosyltransferase Inhibitors
por: Tanuma, Sei-ichi, et al.
Publicado: (2020)

Nicotinamide Phosphoribosyltransferase as a Key Molecule of the Aging/Senescence Process
por: Khaidizar, Fiqri D., et al.
Publicado: (2021)

Nicotinamide phosphoribosyltransferase as a biomarker for the diagnosis of infectious pleural effusions
por: Huang, Jing, et al.
Publicado: (2021)

Nicotinamide phosphoribosyltransferase regulates the cell differentiation and mineralization in cultured odontoblasts
por: Kang, Kyeong-Rok, et al.
Publicado: (2022)

Anticancer Activities of Novel Nicotinamide Phosphoribosyltransferase Inhibitors in Hematological Malignancies
por: Biniecka, Paulina, et al.
Publicado: (2023)

Extracellular nicotinamide phosphoribosyltransferase: role in disease pathophysiology and as a biomarker
por: Semerena, Elise, et al.
Publicado: (2023)

Leucocytes are a major source of circulating nicotinamide phosphoribosyltransferase (NAMPT)/pre-B cell colony (PBEF)/visfatin linking obesity and inflammation in humans
por: Friebe, D., et al.
Publicado: (2011)

Associations between Tissue Visfatin/Nicotinamide, Phosphoribosyltransferase (Nampt), Retinol Binding Protein-4, and Vaspin Concentrations and Insulin Resistance in Morbidly Obese Subjects
por: Goktas, Zeynep, et al.
Publicado: (2013)

New Insights into the Phylogeny and Molecular Classification of Nicotinamide Mononucleotide Deamidases
por: Sánchez-Carrón, Guiomar, et al.
Publicado: (2013)

Slc12a8 is a nicotinamide mononucleotide transporter
por: Grozio, Alessia, et al.
Publicado: (2019)

Subacute Toxicity Study of Nicotinamide Mononucleotide via Oral Administration
por: You, Yingnan, et al.
Publicado: (2020)

Administration of nicotinamide mononucleotide improves oocyte quality of obese mice
por: Wang, Luyao, et al.
Publicado: (2022)

Oral Administration of Nicotinamide Mononucleotide Is Safe and Efficiently Increases Blood Nicotinamide Adenine Dinucleotide Levels in Healthy Subjects
por: Okabe, Keisuke, et al.
Publicado: (2022)

Nicotinamide Phosphoribosyltransferase (Nampt)/Nicotinamide Adenine Dinucleotide (NAD) Axis Suppresses Atrial Fibrillation by Modulating the Calcium Handling Pathway
por: Feng, Duo, et al.
Publicado: (2020)

Discovery and characterization of novel small-molecule inhibitors targeting nicotinamide phosphoribosyltransferase
por: Xu, Tian-Ying, et al.
Publicado: (2015)

Nicotinamide Phosphoribosyltransferase Inhibitor as a Novel Payload for Antibody–Drug Conjugates
por: Karpov, Alexei S., et al.
Publicado: (2018)

Clickable prodrugs bearing potent and hydrolytically cleavable nicotinamide phosphoribosyltransferase inhibitors
por: Sadrerafi, Keivan, et al.
Publicado: (2018)

Nicotinamide Phosphoribosyltransferase Attenuates Methotrexate Response in Juvenile Idiopathic Arthritis and In Vitro
por: Funk, RS, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_udnhrr0h70istsin601o5jh5mg