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Checkpoints in Adenoviral Production: Cross-Contamination and E1A

Adenoviruses are widely used for overexpressing proteins in primary mammalian cells. Incorporation of the early viral gene, E1A, or viral cross-contamination can occur during amplification, and identification of these products is crucial as the transcription of unwanted genetic material can impact c...

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Detalles Bibliográficos
Autores principales: Haeussler, Dagmar J., Evangelista, Alicia M., Burgoyne, Joseph R., Cohen, Richard A., Bachschmid, Markus M., Pimental, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149638/
https://www.ncbi.nlm.nih.gov/pubmed/21826235
http://dx.doi.org/10.1371/journal.pone.0023160