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Modulation of Glucose Transporter 1 (GLUT1) Expression Levels Alters Mouse Mammary Tumor Cell Growth In Vitro and In Vivo

Tumor cells exhibit an altered metabolism characterized by elevated aerobic glycolysis and lactate secretion which is supported by an increase in glucose transport and consumption. We hypothesized that reducing or eliminating the expression of the most prominently expressed glucose transporter(s) wo...

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Detalles Bibliográficos
Autores principales: Young, Christian D., Lewis, Andrew S., Rudolph, Michael C., Ruehle, Marisa D., Jackman, Matthew R., Yun, Ui J., Ilkun, Olesya, Pereira, Renata, Abel, E. Dale, Anderson, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149640/
https://www.ncbi.nlm.nih.gov/pubmed/21826239
http://dx.doi.org/10.1371/journal.pone.0023205