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Modulation of Glucose Transporter 1 (GLUT1) Expression Levels Alters Mouse Mammary Tumor Cell Growth In Vitro and In Vivo
Tumor cells exhibit an altered metabolism characterized by elevated aerobic glycolysis and lactate secretion which is supported by an increase in glucose transport and consumption. We hypothesized that reducing or eliminating the expression of the most prominently expressed glucose transporter(s) wo...
Autores principales: | Young, Christian D., Lewis, Andrew S., Rudolph, Michael C., Ruehle, Marisa D., Jackman, Matthew R., Yun, Ui J., Ilkun, Olesya, Pereira, Renata, Abel, E. Dale, Anderson, Steven M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149640/ https://www.ncbi.nlm.nih.gov/pubmed/21826239 http://dx.doi.org/10.1371/journal.pone.0023205 |
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