Is CFTR-delF508 Really Absent from the Apical Membrane of the Airway Epithelium?

BACKGROUND: Understanding where mutant CFTR is localised in airway epithelia is essential in guiding the best therapeutic approach to correct the dysfunction of the CFTR protein. The widely held paradigm is that CF patients harbouring the commonest mutation, CFTR-delF508, trap CFTR within the endopl...

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Detalles Bibliográficos
Autores principales: Borthwick, Lee A., Botha, Phil, Verdon, Bernard, Brodlie, Malcolm J., Gardner, Aaron, Bourn, David, Johnson, Gail E., Gray, Mike A., Fisher, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149652/
https://www.ncbi.nlm.nih.gov/pubmed/21826241
http://dx.doi.org/10.1371/journal.pone.0023226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149652/
https://www.ncbi.nlm.nih.gov/pubmed/21826241
http://dx.doi.org/10.1371/journal.pone.0023226

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