Role for inducible cAMP early repressor in promoting pancreatic beta cell dysfunction evoked by oxidative stress in human and rat islets

AIMS/HYPOTHESIS: Pro-atherogenic and pro-oxidant, oxidised LDL trigger adverse effects on pancreatic beta cells, possibly contributing to diabetes progression. Because oxidised LDL diminish the expression of genes regulated by the inducible cAMP early repressor (ICER), we investigated the involvemen...

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Detalles Bibliográficos
Autores principales: Favre, D., Niederhauser, G., Fahmi, D., Plaisance, V., Brajkovic, S., Beeler, N., Allagnat, F., Haefliger, J. A., Regazzi, R., Waeber, G., Abderrahmani, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149674/
https://www.ncbi.nlm.nih.gov/pubmed/21547497
http://dx.doi.org/10.1007/s00125-011-2165-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149674/
https://www.ncbi.nlm.nih.gov/pubmed/21547497
http://dx.doi.org/10.1007/s00125-011-2165-x

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