Cargando…

Role for inducible cAMP early repressor in promoting pancreatic beta cell dysfunction evoked by oxidative stress in human and rat islets

AIMS/HYPOTHESIS: Pro-atherogenic and pro-oxidant, oxidised LDL trigger adverse effects on pancreatic beta cells, possibly contributing to diabetes progression. Because oxidised LDL diminish the expression of genes regulated by the inducible cAMP early repressor (ICER), we investigated the involvemen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Favre, D., Niederhauser, G., Fahmi, D., Plaisance, V., Brajkovic, S., Beeler, N., Allagnat, F., Haefliger, J. A., Regazzi, R., Waeber, G., Abderrahmani, A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149674/ https://www.ncbi.nlm.nih.gov/pubmed/21547497 http://dx.doi.org/10.1007/s00125-011-2165-x

Ejemplares similares

Role of MicroRNAs in Islet Beta-Cell Compensation and Failure during Diabetes
por: Plaisance, Valérie, et al.
Publicado: (2014)

Impaired Expression of the Inducible cAMP Early Repressor Accounts for Sustained Adipose CREB Activity in Obesity
por: Favre, Dimitri, et al.
Publicado: (2011)

Islet Brain 1 Protects Insulin Producing Cells against Lipotoxicity
por: Brajkovic, Saška, et al.
Publicado: (2016)

Reduction of Connexin36 Content by ICER-1 Contributes to Insulin-Secreting Cells Apoptosis Induced by Oxidized LDL Particles
por: Haefliger, Jacques-Antoine, et al.
Publicado: (2013)

Ghrelin Attenuates cAMP-PKA Signaling to Evoke Insulinostatic Cascade in Islet β-Cells
por: Dezaki, Katsuya, et al.
Publicado: (2011)

Evidence for tuning adipocytes ICER levels for obesity care
por: Brajkovic, Saška, et al.
Publicado: (2012)

Inducible cAMP Early Repressor (ICER) and Brain Functions
por: Borlikova, Gilyana, et al.
Publicado: (2009)

Endoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDL
por: Plaisance, Valérie, et al.
Publicado: (2016)

Role of microRNAs in the age-associated decline of pancreatic beta cell function in rat islets
por: Tugay, Ksenia, et al.
Publicado: (2015)

Specific Silencing of the REST Target Genes in Insulin-Secreting Cells Uncovers Their Participation in Beta Cell Survival
por: Martin, David, et al.
Publicado: (2012)

Compensatory Mechanisms of Pancreatic Beta Cells: Insights into the Therapeutic Perspectives for Diabetes
por: Regazzi, Romano, et al.
Publicado: (2014)

Inhibitory Role of Inducible cAMP Early Repressor (ICER) in Methamphetamine-Induced Locomotor Sensitization
por: Han, Wenhua, et al.
Publicado: (2011)

The psychosis risk factor RBM12 encodes a novel repressor of GPCR/cAMP signal transduction
por: Semesta, Khairunnisa M, et al.
Publicado: (2023)

The psychosis risk factor RBM12 encodes a novel repressor of GPCR/cAMP signal transduction
por: Semesta, Khairunnisa M., et al.
Publicado: (2023)

Rolipram, a Phosphodiesterase 4 Inhibitor, Stimulates Inducible cAMP Early Repressor Expression in Osteoblasts
por: Cho, Eun Sook, et al.
Publicado: (2005)

Impaired histone deacetylases 5 and 6 expression mimics the effects of obesity and hypoxia on adipocyte function
por: Bricambert, Julien, et al.
Publicado: (2016)

Phosphodiesterase beta is the master regulator of cAMP signalling during malaria parasite invasion
por: Flueck, Christian, et al.
Publicado: (2019)

Beta-Endorphin 1–31 Biotransformation and cAMP Modulation in Inflammation
por: Asvadi, Naghmeh Hajarol, et al.
Publicado: (2014)

The Role of cAMP in Beta Cell Stimulus–Secretion and Intercellular Coupling
por: Stožer, Andraž, et al.
Publicado: (2021)

MyRIP interaction with MyoVa on secretory granules is controlled by the cAMP-PKA pathway
por: Brozzi, Flora, et al.
Publicado: (2012)

Glucose- and Hormone-Induced cAMP Oscillations in α- and β-Cells Within Intact Pancreatic Islets
por: Tian, Geng, et al.
Publicado: (2011)

Leucine suppresses glucagon secretion from pancreatic islets by directly modulating α-cell cAMP
por: Knuth, Emily R., et al.
Publicado: (2023)

Multiple Facets of cAMP Signalling and Physiological Impact: cAMP Compartmentalization in the Lung
por: Oldenburger, Anouk, et al.
Publicado: (2012)

cAMP crosses junctions
por: Bashyam, Hema
Publicado: (2007)

Mitochondrial cAMP signaling
por: Zhang, Fan, et al.
Publicado: (2016)

Correction: The GTPase Rab37 Participates in the Control of Insulin Exocytosis
por: Ljubicic, Sanda, et al.
Publicado: (2013)

Regulation of Inositol 1,4,5-Trisphosphate Receptors by cAMP Independent of cAMP-dependent Protein Kinase
por: Tovey, Stephen C., et al.
Publicado: (2010)

Polymer-Based Nanostructures for Pancreatic Beta-Cell Imaging and Non-Invasive Treatment of Diabetes
por: Behzadifar, Shakila, et al.
Publicado: (2023)

Mechanisms Restricting Diffusion of Intracellular cAMP
por: Agarwal, Shailesh R., et al.
Publicado: (2016)

Cyclic 3', 5'-AMP relay in dictyostelium discoideum. IV. Recovery of the cAMP signaling response after adaptation to cAMP
por: Dinauer, M, et al.
Publicado: (1980)

Cyclic 3', 5'-AMP relay dictyostelium discoideum. V. Adaptation of the cAMP signaling response during cAMP stimulation
por: Dinauer, M, et al.
Publicado: (1980)

Suppression of Virulence of Toxigenic Vibrio cholerae by Anethole through the Cyclic AMP (cAMP)-cAMP Receptor Protein Signaling System
por: Zahid, M. Shamim Hasan, et al.
Publicado: (2015)

Imaging cAMP nanodomains in the heart
por: Chao, Ying-Chi, et al.
Publicado: (2019)

cAMP is an allosteric modulator of DNA-binding specificity in the cAMP receptor protein from Mycobacterium tuberculosis
por: Gárate, Fernanda, et al.
Publicado: (2021)

An Improved Genetically Encoded Fluorescent cAMP Indicator for Sensitive cAMP Imaging and Fast Drug Screening
por: Liu, Wenfeng, et al.
Publicado: (2022)

Regulation of colonic apical potassium (BK) channels by cAMP and somatostatin
por: Perry, M. D., et al.
Publicado: (2009)

Sleep deprivation impairs cAMP signaling in the hippocampus
por: Vecsey, Christopher G., et al.
Publicado: (2009)

Cyclic 3',5'-AMP relay in Dictyostelium discoideum III. The relationship of cAMP synthesis and secretion during the cAMP signaling response
Publicado: (1980)

Direct regulation of the natural competence regulator gene tfoX by cyclic AMP (cAMP) and cAMP receptor protein (CRP) in Vibrios
por: Wu, Rui, et al.
Publicado: (2015)

The COX-2/PGE(2)/EP3/G(i/o)/cAMP/GSIS Pathway in the Islet: The Beat Goes On
por: Robertson, R. Paul
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_h51mq0sfdj2tqdld9v4rh991bh