In vitro epithelial-to-mesenchymal transformation in human adult epicardial cells is regulated by TGFβ-signaling and WT1

Adult epicardial cells are required for endogenous cardiac repair. After myocardial injury, they are reactivated, undergo epithelial-to-mesenchymal transformation (EMT) and migrate into the injured myocardium where they generate various cell types, including coronary smooth muscle cells and cardiac...

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Detalles Bibliográficos
Autores principales: Bax, Noortje A. M., van Oorschot, Angelique A. M., Maas, Saskia, Braun, Jerry, van Tuyn, John, de Vries, Antoine A. F., Groot, Adriana C. Gittenberger-de, Goumans, Marie-José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149675/
https://www.ncbi.nlm.nih.gov/pubmed/21516490
http://dx.doi.org/10.1007/s00395-011-0181-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149675/
https://www.ncbi.nlm.nih.gov/pubmed/21516490
http://dx.doi.org/10.1007/s00395-011-0181-0

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