Cargando…

In vitro epithelial-to-mesenchymal transformation in human adult epicardial cells is regulated by TGFβ-signaling and WT1

Adult epicardial cells are required for endogenous cardiac repair. After myocardial injury, they are reactivated, undergo epithelial-to-mesenchymal transformation (EMT) and migrate into the injured myocardium where they generate various cell types, including coronary smooth muscle cells and cardiac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bax, Noortje A. M., van Oorschot, Angelique A. M., Maas, Saskia, Braun, Jerry, van Tuyn, John, de Vries, Antoine A. F., Groot, Adriana C. Gittenberger-de, Goumans, Marie-José
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2011
Materias:	Original Contribution
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149675/ https://www.ncbi.nlm.nih.gov/pubmed/21516490 http://dx.doi.org/10.1007/s00395-011-0181-0

Ejemplares similares

Epithelial-to-mesenchymal transformation alters electrical conductivity of human epicardial cells
por: Bax, Noortje A M, et al.
Publicado: (2011)

Origin, Fate, and Function of Epicardium-Derived Cells (EPDCs) in Normal and Abnormal Cardiac Development
por: Lie-Venema, Heleen, et al.
Publicado: (2007)

Regional differences in WT-1 and Tcf21 expression during ventricular development: implications for myocardial compaction
por: Vicente-Steijn, Rebecca, et al.
Publicado: (2015)

Discordant phenotypes in monozygotic twins with identical de novo WT1 mutation
por: Yu, Zihua, et al.
Publicado: (2012)

Epicardial TGFβ and BMP Signaling in Cardiac Regeneration: What Lesson Can We Learn from the Developing Heart?
por: Dronkers, Esther, et al.
Publicado: (2020)

Cardiomyogenic differentiation-independent improvement of cardiac function by human cardiomyocyte progenitor cell injection in ischaemic mouse hearts
por: den Haan, Melina C, et al.
Publicado: (2012)

Low oxygen tension positively influences cardiomyocyte progenitor cell function
por: van Oorschot, Angelique A M, et al.
Publicado: (2011)

Active Wnt signaling in response to cardiac injury
por: Oerlemans, Martinus I. F. J., et al.
Publicado: (2010)

Developmental patterns and characteristics of epicardial cell markers Tbx18 and Wt1 in murine embryonic heart
por: Zeng, Bin, et al.
Publicado: (2011)

The Transcription Factors Tbx18 and Wt1 Control the Epicardial Epithelial-Mesenchymal Transition through Bi-Directional Regulation of Slug in Murine Primary Epicardial Cells
por: Takeichi, Makiko, et al.
Publicado: (2013)

Wall Shear Stress Directional Abnormalities in BAV Aortas: Toward a New Hemodynamic Predictor of Aortopathy?
por: Grewal, Nimrat, et al.
Publicado: (2019)

Activin A and ALK4 Identified as Novel Regulators of Epithelial to Mesenchymal Transition (EMT) in Human Epicardial Cells
por: Dronkers, Esther, et al.
Publicado: (2021)

B-vitamins and body composition: integrating observational and experimental evidence from the B-PROOF study
por: Oliai Araghi, Sadaf, et al.
Publicado: (2019)

Cardiac Development
por: Poelmann, Robert E., et al.
Publicado: (2008)

Hemodynamics in Cardiac Development
por: Poelmann, Robert E., et al.
Publicado: (2018)

Development and evolution of the metazoan heart
por: Poelmann, Robert E., et al.
Publicado: (2019)

Human fetal and adult epicardial-derived cells: a novel model to study their activation
por: Moerkamp, Asja T., et al.
Publicado: (2016)

The association between adherence to a plant-based diet and cognitive ageing
por: van Soest, Annick P. M., et al.
Publicado: (2023)

Mimicking Cardiac Fibrosis in a Dish: Fibroblast Density Rather than Collagen Density Weakens Cardiomyocyte Function
por: van Spreeuwel, Ariane C.C., et al.
Publicado: (2017)

Increasing heart vascularisation after myocardial infarction using brain natriuretic peptide stimulation of endothelial and WT1(+) epicardial cells
por: Li, Na, et al.
Publicado: (2020)

DHA status influences effects of B-vitamin supplementation on cognitive ageing: a post-hoc analysis of the B-proof trial
por: van Soest, Annick P. M., et al.
Publicado: (2022)

Epicardial Electric Activation During Atrial Fibrillation
por: Kharbanda, Rohit K., et al.
Publicado: (2020)

Bicuspid aortic valve formation: Nos3 mutation leads to abnormal lineage patterning of neural crest cells and the second heart field
por: Peterson, Joshua C., et al.
Publicado: (2018)

In vivo and in vitro Approaches Reveal Novel Insight Into the Ability of Epicardium-Derived Cells to Create Their Own Extracellular Environment
por: Bax, Noortje A. M., et al.
Publicado: (2019)

BRG1-SWI/SNF-dependent regulation of the Wt1 transcriptional landscape mediates epicardial activity during heart development and disease
por: Vieira, Joaquim Miguel, et al.
Publicado: (2017)

Exploring the association between whole blood Omega-3 Index, DHA, EPA, DHA, AA and n-6 DPA, and depression and self-esteem in adolescents of lower general secondary education
por: van der Wurff, I. S. M., et al.
Publicado: (2018)

Epicardial and endothelial cell activation concurs with extracellular matrix remodeling in atrial fibrillation
por: van den Berg, Nicoline W. E., et al.
Publicado: (2021)

‘I am your son, mother’: severe dementia and duties to visit parents who can’t recognise you
por: de Vries, Bouke
Publicado: (2019)

Why visiting one’s ageing mother is not enough: on filial duties to prevent and alleviate parental loneliness
por: de Vries, Bouke
Publicado: (2021)

Normal and abnormal development of the aortic wall and valve: correlation with clinical entities
por: Grewal, N., et al.
Publicado: (2014)

Disturbed nitric oxide signalling gives rise to congenital bicuspid aortic valve and aortopathy
por: Peterson, Joshua C., et al.
Publicado: (2020)

Age-dependent alteration of TGF-β signalling in osteoarthritis
por: van der Kraan, Peter M., et al.
Publicado: (2011)

Brain Activity and Cerebral Oxygenation After Perinatal Arterial Ischemic Stroke Are Associated With Neurodevelopment
por: Wagenaar, Nienke, et al.
Publicado: (2019)

Maternal depressive symptoms during pregnancy are associated with amygdala hyperresponsivity in children
por: van der Knaap, Noortje J. F., et al.
Publicado: (2017)

Efficient Differentiation of TBX18(+)/WT1(+) Epicardial-Like Cells from Human Pluripotent Stem Cells Using Small Molecular Compounds
por: Zhao, Jianmin, et al.
Publicado: (2017)

Normalization of Cardiac Function After Bariatric Surgery Is Related to Autonomic Function and Vitamin D
por: Snelder, Sanne M., et al.
Publicado: (2022)

The Influence of Body Contouring Surgery on Weight Control and Comorbidities in Patients After Bariatric Surgery
por: de Vries, C. E. E., et al.
Publicado: (2019)

Low vitamin D status is associated with more depressive symptoms in Dutch older adults
por: Brouwer-Brolsma, E. M., et al.
Publicado: (2015)

Demographics and gender-related measures in younger and older adolescents presenting to a gender service
por: Arnoldussen, Marijn, et al.
Publicado: (2022)

Patient Selection for Epicardial Ablation—Part II: The Epicardial Approach and Current Challenges Associated with Epicardial Ablation
por: Edward, Justin A., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_i1u5do5j6o2c49d25jbd4ul94u