Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

The three-dimensional folding of chromosomes compartmentalizes the genome and and can bring distant functional elements, such as promoters and enhancers, into close spatial proximity (2-6). Deciphering the relationship between chromosome organization and genome activity will aid in understanding gen...

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Detalles Bibliográficos
Autores principales: van Berkum, Nynke L., Lieberman-Aiden, Erez, Williams, Louise, Imakaev, Maxim, Gnirke, Andreas, Mirny, Leonid A., Dekker, Job, Lander, Eric S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2010
Materias:
Cellular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149993/
https://www.ncbi.nlm.nih.gov/pubmed/20461051
http://dx.doi.org/10.3791/1869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149993/
https://www.ncbi.nlm.nih.gov/pubmed/20461051
http://dx.doi.org/10.3791/1869

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